摘要 |
<p>NEW MATERIAL:A compound shown by the formula I (R<1> is H, or OH-protecting group; X is carbonyl, alkoxycarbonyl, cyano, substituted thio, sulfoxy or sulfonyl, substituted phosphoryl, substituted alkynyl, nitro, isonitrile, or acyl). EXAMPLE:[2R, 3S]-1,4-Bis[{3-[1-(R)-hydroxyethyl}-2-phenylsulfonyl-4-oxo]azetidinon- 1-yl]benzene. USE:An intermediate for synthesizing a thienamycin compound. PREPARATION:For example, a compound shown by the formula II is treated with a base, to give a compound shown by the formula III where R<1> is H in the formula I . The compound shown by the formula II is obtained from a compound shown by the formula IV through a compound shown by the formula Vand a compound shown by the formula VI.</p> |