发明名称 REGION SPECIFIC PROTEASE BY LENIN
摘要 A nucleotide sequence which codes for an amino acid sequence specifically recognized and cleaved by the endopeptidase, renin, has been inserted into a plasmid expression vector. This nucleotide sequence was placed within a sequence of DNA, at the junction between the sequences coding for two distinct domains of a fusion protein. The resultant novel protein product expressed by the new construction can be specifically cleaved by renin to yield two distinct proteins corresponding to the two domains of the original fusion protein product.
申请公布号 JPS60262595(A) 申请公布日期 1985.12.25
申请号 JP19850110614 申请日期 1985.05.24
申请人 MERCK & CO INC 发明人 JIYOSHIYUA ESU BOJIYAA;MEARI ERU HATSUFUEI;EDOWAADO EMU SUKORUNIKU
分类号 C12N15/09;C07H21/04;C07K7/14;C07K14/05;C12N1/00;C12N9/48;C12N15/62;C12R1/19 主分类号 C12N15/09
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