| 摘要 |
The invention provides an in vitro method for the diagnosis of dementia with Lewy bodies comprising detecting, in a biological sample from a subject, at least one variation in SEQ ID NO: 14, or alternatively at least one variation in SEQ ID NO: 15, or alternatively at least one variation in SEQ ID NO: 16, wherein SEQ ID NO: 14, SEQ ID NO: 15 and SEQ ID NO: 16 are comprised within position 175.989.261 to position 176.003.107 in Homo sapiens chromosome 5 according to HapMap data release 28 (SEQ ID NO: 1). The invention also provides means for detecting the above variations and a method for recommending to initiate a medical regime for the treatment of DLB in a subject based on detecting the above variations. In particular, the provided method is for the in vitro diagnosis of pure dementia with Lewy bodies. |
