| 摘要 |
<p>A process for preparing alpha substituted epoxides is provided. The process comprises contacting alcohols of formula (R<2>)(R<1>)(HO)C-CG(R<3>)X with a dihydrocarbyl peroxide, a copper compound and a Lewis base to yield compounds of formula <CHEM> R<1>, R<2>, R<3> and R<4> can be hydrogen, alkyl, cycloalkyl or aromatic radicals whilst X is selected from COR<4>, CN COOR<4> or CONR<4>2 groups. The process can be used for converting diacetone alcohol to its corresponding alpha substituted epoxide.</p> |
