Oral dosage form containing a PDE 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient

摘要

Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder.

主权项

1. A solid dosage form in tablet or pellet form for the oral administration of roflumilast, comprising: roflumilast—0.250 mg; lactose monohydrate—49.660 mg; corn starch—13.390 mg; polyvinylpyrrolidone having a weight average molecular weight of between 1,000,000 and 1,500,000-1.300 mg; and magnesium stearate—0.650 mg and wherein said dosage form provides immediate release of said roflumilast.