发明名称 |
W-ARYLSULPHONAMIDOALKANOIC ACIDS FOR TREATMENT OF THROMBOXANE MEDIATED DISEASES |
摘要 |
The present invention provides the use of a compound of the formula (I): RSO2NR min BCO2H (I) or a salt or ester thereof, wherein R is a phenyl, furan or thiophene ring optionally substituted by one or more substituents which are the same or different and are chosen from halogen, nitro, cyano, trifluoromethyl, C1-4alkyl and C1-4alkoxy; R min is hydrogen or C1-4alkyl; and B is an acyclic hydrocarbon group having 4 to 11 linear carbon atoms, any one or more of the linear carbon atoms of which are optionally substituted by one or two C1-3alkyl groups; in the preparation of a medicament for the treatment of thromboxane mediated diseases. Also provided are novel compounds of the formula (I), compositions containing them and processes for their preparation. |
申请公布号 |
WO8901330(A3) |
申请公布日期 |
1989.05.05 |
申请号 |
WO1988GB00674 |
申请日期 |
1988.08.16 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED;BOEHRINGER MANNHEIM GMBH |
发明人 |
IFE, ROBERT, JOHN;COOPER, DAVID, GWYN;SLATER, ROBERT, ANTONY;STEGMEIER, KARLHEINZ;WITTE, ERNST-CHRISTIAN |
分类号 |
A61K31/195;A61K31/19;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/63;A61P7/02;C07C303/36;C07C311/19;C07C311/29;C07D307/64;C07D333/34 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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