发明名称 W-ARYLSULPHONAMIDOALKANOIC ACIDS FOR TREATMENT OF THROMBOXANE MEDIATED DISEASES
摘要 The present invention provides the use of a compound of the formula (I): RSO2NR min BCO2H (I) or a salt or ester thereof, wherein R is a phenyl, furan or thiophene ring optionally substituted by one or more substituents which are the same or different and are chosen from halogen, nitro, cyano, trifluoromethyl, C1-4alkyl and C1-4alkoxy; R min is hydrogen or C1-4alkyl; and B is an acyclic hydrocarbon group having 4 to 11 linear carbon atoms, any one or more of the linear carbon atoms of which are optionally substituted by one or two C1-3alkyl groups; in the preparation of a medicament for the treatment of thromboxane mediated diseases. Also provided are novel compounds of the formula (I), compositions containing them and processes for their preparation.
申请公布号 WO8901330(A3) 申请公布日期 1989.05.05
申请号 WO1988GB00674 申请日期 1988.08.16
申请人 SMITH KLINE & FRENCH LABORATORIES LIMITED;BOEHRINGER MANNHEIM GMBH 发明人 IFE, ROBERT, JOHN;COOPER, DAVID, GWYN;SLATER, ROBERT, ANTONY;STEGMEIER, KARLHEINZ;WITTE, ERNST-CHRISTIAN
分类号 A61K31/195;A61K31/19;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/63;A61P7/02;C07C303/36;C07C311/19;C07C311/29;C07D307/64;C07D333/34 主分类号 A61K31/195
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