发明名称 |
PELLET PREPARATION |
摘要 |
<p>1. Sustained-release formulation of acemetacin based on encapsulated multiple unit doses in the form of pellets containing a physiologpally innocuous substance of relatively high specific gravity, characterized in that it consists of an initial dose which contains 10 to 60% by weight of the total amount of acemetacin and if appropriate additives, and a pellet formulation which contains the remaining amount of the active compound, a disintegrating agent, a binder and a substance having a relatively high specific gravity and is coated with a lacquer which is resistant to gastric juice, the individual pellets having a diameter of 0.2 to 1.8 mm.</p> |
申请公布号 |
EP0173210(B1) |
申请公布日期 |
1990.05.16 |
申请号 |
EP19850110362 |
申请日期 |
1985.08.19 |
申请人 |
TROPONWERKE GMBH & CO. KG |
发明人 |
DELL, HANS-DIETER, DR.;KRAUS, REINHOLD;SCHIERSTEDT, DETLEF, DR. |
分类号 |
A61K9/16;A61K9/20;A61K9/22;A61K9/48;A61K9/50;A61K9/52;A61K31/405 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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