发明名称 FRAMSTAELLNING AV SUBSTITUERADE ETENER
摘要 A potassium salt useful in the production of N-substituted-1-alkylthio-2-nitroethenamines is produced by the reaction of the dipotassium salt of nitrodithioacetic acid with certain straight chain alkylamines, thereby converting only one of the KS-groups to an alkylamine group. The resulting monopotassium salt may be alkylated to produce the required N-substituted-1-alkylthio compound which may be reacted with a suitable amine to produce the histamine H2-antagonist ranitidine.
申请公布号 SE9001236(L) 申请公布日期 1990.10.06
申请号 SE19900001236 申请日期 1990.04.04
申请人 FINE ORGANICS LTD 发明人 GRAYSON J I
分类号 C07D307/52;B01J35/12;C07B61/00;C07C319/14;C07C319/22;C07C323/24;C07C323/27;C07D307/38;C07D317/58;C07D407/12;(IPC1-7):C07C319/22 主分类号 C07D307/52
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