| 发明名称 | Molecularly imprinted polymers | ||
| 摘要 | The present invention refers to new classes of polymerizable monomers targeting biotin, a biotin derivative, a biotin analog or a biotinylated molecule and related structures, as well as molecularly imprinted polymers obtainable by polymerization of at least one of these monomers and at least one cross-linking monomer in the presence of a suitable template molecule. The obtained polymers may be used for separation of biotin and related small molecules, together with larger biotinylated molecules of biological origin, e.g. proteins, from complex mixtures. The monomer comprises i) an isophthalic acid derivative or a pyridine-2,6-dicarboxylic acid derivative and ii) a vinyl-2-aminopyridine derivative. | ||
| 申请公布号 | US9464150(B2) | 申请公布日期 | 2016.10.11 |
| 申请号 | US201314423208 | 申请日期 | 2013.08.22 |
| 申请人 | The University of Kent | 发明人 | Hall Andrew |
| 分类号 | C08F222/14;C07D213/75;C08F226/06;G01N33/82 | 主分类号 | C08F222/14 |
| 代理机构 | Bookoff McAndrews, PLLC | 代理人 | Bookoff McAndrews, PLLC |
| 主权项 | 1. A polymerisable monomer comprising a recognition cleft for biotin, a biotin derivative, a biotin analogue or a biotinylated molecule, the monomer comprising i) an isophthalic acid derivative or a pyridine-2,6-dicarboxylic acid derivative and ii) a vinyl-2-aminopyridine derivative for use as part of a molecularly imprinted polymer. | ||
| 地址 | Chatham, Kent GB | ||