发明名称 DERIVES DE PYRROLE UTILISABLES NOTAMMENT COMME INTERCEPTEURS D'ESPECES ACTIVEES DU DIOXYGENE - LEUR PROCEDE DE PREPARATION - COMPOSITIONS LES CONTENANT
摘要 The pyrrol derivates correspond to the formula (I) in which R is an amino acid derivate, a non-proteinic peptide derivate, an osamine derivate, or a derivate of a purine base or a pyrimidic base with a free NH2 group, the pyrimidic bases being replaced by at least one -SH group, R1 is an alkyl, if necessary a substituted amine, a -SH group, possibly substituted, a primary, secondary, or tertiary alcohol, the corresponding ethers and esters, a cyclic radical or heterocycle, the salts and complexes with physiologically acceptable metals, on condition that R1 is different from hydrogen when R is a derivate of glycine, leucine, phenylalanine, tyrosin, serine, or glutamic acid. Said derivates are useful in therapeutic and cosmetic applications.
申请公布号 FR2647674(A1) 申请公布日期 1990.12.07
申请号 FR19890007475 申请日期 1989.06.06
申请人 CENTRE NAL RECHERC SCIENTIFIQUE 发明人 ALAIN VALLA;MICHEL GIRAUD;MARC BAZIN;RENE SANTUS
分类号 A61K8/49;A61K8/64;A61Q19/00;A61Q19/08;C07D207/32;C07D207/327;C07D403/04;C07D403/06;C07D403/12;C07D473/34 主分类号 A61K8/49
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