摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing (2E, 6E)-farnesal useful as an intermediate for the production of a polyisoprenoid derivative useful as an anticancer agent.SOLUTION: The method for producing (2E, 6E)-farnesal includes heating (2Z, 6E)-farnesal in the presence of a piperidin-1-oxyl compound represented by formula (1) [wherein Ris a hydrogen atom; Ris a hydrogen atom, cyano, carboxy, isothiocyanato, maleimide, phosphate group, -OR' group or -NHR" group (wherein R' is a hydrogen atom, 1-4C alkyl, acyl or 1-4C alkanesulfonyl; R" is a hydrogen atom, acetyl or haloacetyl); or Rand Rtogether form an oxo group]. |