发明名称 Substituted 3,4-dihydro-2H-benzopyrans, processes for their preparation, their use and pharmaceutical products based on these compounds
摘要 3,4-Dihydro-2H-benzo[b]pyrans of the formula I <IMAGE> I are described, in which R1 is H, OH, (C1-C2)-alkoxy, (C1-C2)-alkyl or NR4R5, R4 and R5 being identical or different and representing H, (C1-C2)-alkyl or (C1-C3)-alkylcarbonyl, R2 and R3 are identical or different and are alkyl having 1-4 carbon atoms, Ar is an aromatic or heteroaromatic system which is unsubstituted or substituted, n is 1 or 2 and X is a (CH2)r chain which can be interrupted by a heteroatom O, S or NR6, R6 being H or (C1-C4)-alkyl and r being one of the numbers 2, 3, 4 or 5. Processes for the preparation of these compounds, their use and pharmaceutical products based on these compounds are also described.
申请公布号 US4999371(A) 申请公布日期 1991.03.12
申请号 US19880151584 申请日期 1988.02.02
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 ENGLERT, HEINRICH C.;LANG, HANS-JOCHEN;MANIA, DIETER;SCHOELKENS, BERNWARD
分类号 A61K31/40;A61K31/4025;A61K31/443;A61K31/4433;A61K31/445;A61P9/00;A61P9/08;A61P9/10;C07D405/04;C07D409/14 主分类号 A61K31/40
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