Dry immunoassay analytical element comprising monodispersed beads.

摘要

Herein is disclosed an analytical element for immunoassays comprising a support and a spreading layer characterized in that the element contains, a) a first population of relatively large polymeric beads having a diameter in the range of 10 to 200 mu m to facilitate uniform spreading of liquids applied to the element; and b) a second population of relatively small polymeric beads having (i) a diameter in the range of 0.1 to 5 mu m; (ii) receptors covalently bound to the bead surface through surface reactive groups; and (iii) surfaces which are free of residual materials.