Tripeptide compounds having hypotensive activity

摘要

Tripeptides having hypotensive activity, defined by the following general formula: A-B-C-OZ (I) wherein: A represents a residue of L-pyroglutamic acid, L-proline of L-proline bearing a substituent on its amino group wherein R1 is an acyl with a number of carbon atoms in straight chain not higher than 9, a benzyloxycarbonyl group or an alkyloxycarbonyl group; B is an alpha -aminoacide residue derived from one of the natural aminoacids; C is a residue of L-tryptophan (Trp), of L-phenylalanine (Phe) or of L-tyrosine (Tyr); Z is a hydrogen atom or an alkyl group with a number of carbon atoms in straight chain not higher than 9.