| 摘要 |
<p>A novel 1,4-thiazine derivative of general formula (I) and a pharmaceutically acceptable acid addition salt thereof, useful as a cardiotonic, formula (I), wherein R1 and R2 represent each hydrogen or lower alkyl; and R3 represents -E-(CR'R')n-z wherein E represents: (α) or (β), R represents hydrogen or lower alkyl, n represents an integer of 0 to 2, R' and R' represent each hydrogen or lower alkyl, Z represents hydrogen, optionally trifluoromethylated phenyl, pyridyl or (γ), wherein A represents -CO- or -CHOH-, and X and Y represent each independently hydrogen, lower alkyl, lower alkoxy, trifluoromethyl, halogen, nitro, cyano, amino or phenyl, or alternatively X and Y are combined with each other to form methylenedioxy.</p> |
