发明名称 ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF PENEMDERIVATER OG MELLEMPRODUKTER TIL ANVENDELES VED FREMGANGSMAADEN
摘要 This invention relates to phosphorane compounds of the formula wherein Y is hydrogen, ethyl or hydroxyethyl, Q is phenyl or (lower) alkyl, R" is an easily removable ester group and X represents certain organic substituents. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3- position is protected by an easily removable ester protecting group. The compounds of the present invention are of use as intermediates in the preparation of penem compounds having potent antibacterial activity.
申请公布号 DK161520(C) 申请公布日期 1991.12.23
申请号 DK19790005337 申请日期 1979.12.14
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 MENARD, MARCEL;MARTEL, ALAIN
分类号 A61K31/425;A61K31/12;A61K31/397;A61K31/43;A61P31/04;C07D205/08;C07D205/09;C07D209/48;C07D499/00;C07D499/04;C07D499/06;C07D499/88;C07D499/897;C07F7/08;C07F7/10;C07F7/18;C07F9/535;C07F9/568;C07F9/6539;C07F9/6541;C07F9/6558;C07F9/6561 主分类号 A61K31/425
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