发明名称 |
Drop deployment system for crystal growth apparatus |
摘要 |
This invention relates to a crystal growth apparatus (10) generally used for growing protein crystals wherein a vapor diffusion method is used for growing the crystals. In this apparatus, a precipitating solution and a solution containing dissolved crystalline material are stored in separate vials (12, 14), each having a resilient diaphragm (28) across one end and an opening (24) with a puncturable septum (26) thereacross at an opposite end. The vials are placed in receptacles (30) having a manifold (41) with a manifold diaphragm (42) in contact with the vial diaphragm at one end of the receptacle and a hollow needle (36) for puncturing the septum at the other end of the manifold. The needles of each vial communicate with a ball mixer (40) that mixes the precipitate and protein solutions and directs the mixed solution to a drop support (64) disposed in a crystal growth chamber (16), the drop support being a tube with an inner bevelled surface (66) that provides more support for the drop (68) than the tubes of the prior art. A sealable storage region (70) intermediate the drop support and mixer provides storage of the drop (68) and the grown crystals.
|
申请公布号 |
US5078975(A) |
申请公布日期 |
1992.01.07 |
申请号 |
US19900629740 |
申请日期 |
1990.12.18 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION |
发明人 |
RHODES, PERCY H.;SNYDER, ROBERT S.;PUSEY, MARC L. |
分类号 |
C30B7/00;C30B30/08 |
主分类号 |
C30B7/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|