| 摘要 |
H-408-f PIPERAZINE DERIVATIVES Compounds of formula (I) where A is an alkylene chain of 1 or 2 carbon atoms optionally substituted by one or more lower alkyl groups, R is hydrogen or lower alkyl, R1 is an aryl or heteroaryl radical, R2 is a mono- or bicyclic heterocyclic radical, R3 is hydrogen, lower alkyl or hydroxy and R4 is a aryl or heteroaryl radical, and their pharmaceutically acceptable acid addition salts are 5-HT1A binding agents which may be used, for example, for the treatment of CNS - disorders such as anxiety.
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