发明名称 |
VERFAHREN ZUR HERSTELLUNG EINES KOLLOIDALEN, DISPERSIBLEN SYSTEMS VON NANOKAPSELN. |
摘要 |
The process according to the invention comprises: (1) the preparation of a liquid phase consisting essentially of a solution of a substance A in a solvent or in a mixture of solvents, and containing the substance B in solution or as a dispersion, (2) the preparation of a second liquid phase consisting essentially of a non-solvent or a mixture of non-solvents for the substances A and B, and supplemented with one or more surfactants, the solvent or mixture of solvents of the first phase being miscible in all proportions with the non-solvent or mixture of non-solvents of the second phase, (3) the addition of the first phase to the second phase with moderate agitation so as to produce a colloidal suspension of nanocapsules, the wall of which is constituted by the substance A and the core by the substance B, (4) if desired, the removal of all or part of the solvent or the mixture of solvents and of the non-solvent or the mixture of non-solvents so as to produce a colloidal suspension of nanocapsules of the desired concentration or to produce a powder of nanocapsules following the addition of stabilizing substances. |
申请公布号 |
DE3777793(D1) |
申请公布日期 |
1992.04.30 |
申请号 |
DE19873777793 |
申请日期 |
1987.12.28 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), PARIS, FR |
发明人 |
FESSI, HATEM, F-75014 PARIS, FR;PUISIEUX, FRANCIS, F-94700 MAISONS ALFORT, FR;DEVISSAGUET, JEAN-PHILIPPE, F-92200 NEUILLY S/SEINE, FR |
分类号 |
A61K9/50;A61K9/10;A61K9/51;B01J13/00;B01J13/12;(IPC1-7):B01J13/02 |
主分类号 |
A61K9/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|