发明名称 |
Stabilization of the enzyme urate oxidase in liquid form. |
摘要 |
<p>This invention relates to a process for stabilizing the enzyme urate oxidase (commonly known as uricase) in liquid form, and to the relative compositions which can then be obtained, with particular reference to compositions containing a Trinder reagent. According to the process of the invention, uricase can be stabilized in liquid form by adding to the composition containing the enzyme a substituted or unsubstituted dicarboxylic acid containing from 2 to 5 carbon atoms, and preferably 4 or 5. Aspartic acid has shown to be particularly effective in providing said stabilizing activity in liquid uricase compositions containing a Trinder reagent. <IMAGE></p> |
申请公布号 |
EP0513914(A1) |
申请公布日期 |
1992.11.19 |
申请号 |
EP19920201321 |
申请日期 |
1992.05.11 |
申请人 |
INSTRUMENTATION LABORATORY S.R.L. |
发明人 |
D'ALTERIO, MAURIZIO;FRONTINI, DARIO;PAPAGNI, MAURO |
分类号 |
C12N9/06;C12N9/96;C12Q1/26;C12Q1/62 |
主分类号 |
C12N9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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