PYRIDONECARBOXYLATE COMPOUND, PHARMACEUTICAL USE THEREOF, AND SPIRO COMPOUND

摘要

A pyridonecarboxylate compound represented by general formula (I), a pharmaceutical use thereof, and a spiro compound as an intermediate for synthesizing the same, wherein R<1> represents hydrogen, alkyl, etc.; R<2> represents hydrogen or alkyl; X and Y, which may be the same or different, represent each oxygen, sulfur or -NR<8-> represents hydrogen, alkyl, etc.; l and m represent each an integer of 0 to 3; n represents an integer of 0, 1 or 2; and Q represents a group of general formula (IV), wherein R<9> represents alkyl; R<10> represents hydrogen; R<11> represents -COOR<13> wherein R<13> represents hydrogen, alkyl, etc.; R<12> represents hydrogen, halogen, etc.; Hal represents halogen; and A represents =N- or =CR<14>- wherein R<14> represents hydrogen, halogen, etc.; or alternatively R<9> may be combined with R<10> or R<14> to form a ring, or R<10> may be combined with R<11> to form a ring.