Treatment of diabetic nephropathy

摘要

The present invention is a novel method for the treatment of renal hypertrophy and hyperplasia associated with diabetic nephropathy. The method of the present invention generally comprises the administration to the diabetic patient of a compound which inhibits glycosphingolipid synthesis, more particularly, an inhibitor of GlcCer synthase or 3-ketodihydrosphingosine synthase.