发明名称 Protein for inhibiting collagen-stimulated platelet aggregation
摘要 A protein isolated from crude Haementeria officinalis extract which blocks stimulation of platelet aggregation by collagen. The protein has a molecular weight of approximately 16,000. A method of isolating the protein and using the protein to prevent or delay blood coagulation by blocking the stimulation of platelet aggregation by collagen is also described. The protein is useful in the prevention, prophylaxis, therapy and treatment of thrombotic diseases.
申请公布号 US5324715(A) 申请公布日期 1994.06.28
申请号 US19930044547 申请日期 1993.04.07
申请人 MERCK & CO., INC. 发明人 CONNOLLY, THOMAS M.;KELLER, PAUL M.
分类号 A61K35/62;A61K38/00;A61K38/36;A61P7/02;C07K1/22;C07K1/30;C07K14/435;C07K14/815;C12N1/21;C12N15/09;C12N15/12;C12P21/02;C12R1/865;(IPC1-7):A61K37/00 主分类号 A61K35/62
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