发明名称 PROCESS FOR PREPARING NANOSTRUCTURED BIOMATERIALS OF THE BISMUTH-SUBSTITUTED HYDROXYAPATITE TYPE, FOR MEDICAL APPLICATIONS
摘要 The invention relates to a process for preparing nanostructured biomaterials of the bismuth-substituted hydroxyapatite type, for medical applications. According to the invention, the process consists in mixing an aqueous solution of Bi(NO)x 5HO and Ca(OH)with an aqueous solution of HPO, so that the resulting solution shows a (Ca+Bi)/P molar ratio of 1.67, while maintaining the pH at a constant value of 10.5, the resulting precipitate being left to age for 24 h, at 60°C, while stirring continuously, then separated under vacuum, washed, dried and roasted at 800°C for 1 h, to result in a crystalline yellow powder having a porosity of 40...50% and a pore size of 1.2...2.2 nm.
申请公布号 RO131431(A2) 申请公布日期 2016.10.28
申请号 RO20150000241 申请日期 2015.04.02
申请人 UNIVERSITATEA TEHNICĂ ''GHEORGHE ASACHI'' DIN IAŞI 发明人 CIOBANU MARGARETA-GABRIELA;MATEIUC ANA-MARIA;LUCA CONSTANTIN
分类号 A61K6/06 主分类号 A61K6/06
代理机构 代理人
主权项
地址