Thioalkylthio cephalosporin derivatives

摘要

A novel thioalkylthio cephalosporin antibiotic compound of formula I: <IMAGE> I wherein Acyl is C1-C12 acyl; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms; R1 is a single bond or C1-C4 alkylene; R2 is a straight or branched C1-C4 alkylene; X is a sulfur atom or sulfoxide group; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.