| 摘要 |
Disclosed herein are nucleosides, nucleotides and analogs thereof of formula I, II and III, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof. In particular, viral infections caused by a virus selected from henipavirus, a morbillivirus, a respirovirus, a rubulavirus and a metapneumovirus. |
