发明名称 |
Process for producing trans-L-hydroxyproline |
摘要 |
The present invention provides a process for producing trans-L-hydroxyproline, which comprises culturing a microorganism which is capable of decomposing amino acids other than trans-L-hydroxyproline but which is substantially incapable of decomposing trans-L-hydroxyproline in a culture medium containing collagen hydrolyzate, and recovering trans-L-hydroxyproline from the resulting culture. The process enhances the content of trans-L-hydroxyproline based on the total weight of amino acids contained in collagen hydrolyzate, and enables efficient production of trans-L-hydroxyproline which is useful as a starting material for the synthesis of medicines.
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申请公布号 |
US5364775(A) |
申请公布日期 |
1994.11.15 |
申请号 |
US19920972824 |
申请日期 |
1992.11.06 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
KATSUMATA, RYOICHI;OHSHIRO, TAKASHI;YOKOI, HARUHIKO;SHIOMI, MICHIO |
分类号 |
C12P13/04;C12P13/24;C12R1/01;C12R1/37;(IPC1-7):C12P13/24 |
主分类号 |
C12P13/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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