发明名称 Inklusjonskomplekser i vandige opplösninger av benzotiofenforbindelser med vannopplöselige cyklodekstriner og farmasöytiske formuleringer og fremgangsmåter
摘要 The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
申请公布号 NO944764(D0) 申请公布日期 1994.12.08
申请号 NO19940004764 申请日期 1994.12.08
申请人 LILLY AND CO, ELI 发明人 BRYANT, HENRY UHLMAN;CULLINAN, GEORGE JOSEPH;FRANCIS, PAUL CLIFTON;MAGEE, DAVID EDWARD;SWEETANA, STEPHANIE ANN;THAKKAR, ARVIND LAVJI
分类号 C07D333/56;A61K9/08;A61K31/365;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4535;A61K31/55;A61K47/40;A61K47/48;A61P3/06;A61P7/00;A61P19/08;A61P19/10;A61P43/00;C08B37/16;(IPC1-7):A61K31/38;C08L5/16 主分类号 C07D333/56
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