发明名称 Carbocyclic nucleosides containing bicycle rings, oligonucleotides therefrom, process for their preparation, their use and intermediates
摘要 Compounds of the formulae I and Ia and their racemates <IMAGE> (I) <IMAGE> (Ia) in which A is -CH2- or -CH2CH2-, R1 is hydrogen or a protective group, R2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.
申请公布号 US5461152(A) 申请公布日期 1995.10.24
申请号 US19930083812 申请日期 1993.06.28
申请人 CIBA-GEIGY CORPORATION 发明人 ALTMANN, KARL-HEINZ;IMWINKELRIED, RENE;ESCHENMOSER, ALBERT
分类号 A61K31/435;A61K31/505;A61K31/52;A61K31/522;A61P31/12;C07C215/44;C07C275/50;C07D239/46;C07D239/47;C07D239/48;C07D239/50;C07D239/54;C07D471/04;C07D473/00;C07D473/02;C07D473/16;C07D473/18;C07D473/26;C07D487/04;C07F7/18;C07F9/6512;C07F9/6561;(IPC1-7):C07F9/02;C07D239/02;A61K31/695 主分类号 A61K31/435
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