发明名称 |
Carbocyclic nucleosides containing bicycle rings, oligonucleotides therefrom, process for their preparation, their use and intermediates |
摘要 |
Compounds of the formulae I and Ia and their racemates <IMAGE> (I) <IMAGE> (Ia) in which A is -CH2- or -CH2CH2-, R1 is hydrogen or a protective group, R2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.
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申请公布号 |
US5461152(A) |
申请公布日期 |
1995.10.24 |
申请号 |
US19930083812 |
申请日期 |
1993.06.28 |
申请人 |
CIBA-GEIGY CORPORATION |
发明人 |
ALTMANN, KARL-HEINZ;IMWINKELRIED, RENE;ESCHENMOSER, ALBERT |
分类号 |
A61K31/435;A61K31/505;A61K31/52;A61K31/522;A61P31/12;C07C215/44;C07C275/50;C07D239/46;C07D239/47;C07D239/48;C07D239/50;C07D239/54;C07D471/04;C07D473/00;C07D473/02;C07D473/16;C07D473/18;C07D473/26;C07D487/04;C07F7/18;C07F9/6512;C07F9/6561;(IPC1-7):C07F9/02;C07D239/02;A61K31/695 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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地址 |
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