STEARIC ACID DERIVATIVES AND OLEIC ACID DERIVATIVES OF MULTI-ARM POLYETHYLENE GLYCOL

摘要

Disclosed are multi-arm polyethylene glycol derivatives having structure of formula I or formula VI. Compared with straight chain polyethylene glycol, multi-arm polyethylene glycol has a plurality of terminal groups, thus has a plurality of introducing points of functional groups and can support a plurality of reactive terminal groups, thereby enabling multi-arm polyethylene glycol to have more flexibility and wider range of application.;

主权项

1. A multi-arm polyethylene glycol derivative, wherein the multi-arm polyethylene glycol derivative has a structure of general formula I or general formula VI: wherein: PEG is the same or different and is —(CH2CH2O)m—, m is an integer of 3-250; l is an integer greater than or equal to 1 and less than or equal to 10; X1, X2, X3, X4 are independently selected from the group consisting of the following groups: wherein i is an integer of 0-10; F1, F2, F3, F4 are independently selected from the group consisting of the following groups: and, in general formula I at least one of F1, F2, F3, F4 is or in general formula VI at least one of F1, F2, F4 is