Macrolide compounds

摘要

Compounds of formula (1) and salts thereof, wherein R<1> represents a methyl, ethyl or isopropyl group; Y<1> is -CH2-, Y<2> is -CH- and X represents where R<2> represents a hydrogen atom or a group OR<8> (where OR<8> is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R<3> represents a hydrogen atom, or R<2> and R<3> together with the carbon atom to which they are attached represent >C=0, >C=CH2 or >C=NOR<9> (where R<9> represents a hydrogen atom, a C1-8 alkyl group or a C3-8 alkenyl group) and the group >C=NOR<9> is in the E configuration] or -Y<1>-X-Y<2>- represents -CH=CH-CH- or -CH2-CH=C-; R<4> represents a group OR<8> as defined above and R<5> represents a hydrogen atom, or R<4> and R<5> together with the carbon atom to which they are attached represent >C=0 or >C=NOR<9a> (where R<9a> is as defined above for R<9>); R<6> represents a hydrogen atom and R represents -CH2OH, -CHO, -CO2H or a carboxylic acid ester or amide group; or R<6> represents a hydroxyl group and R represents a methyl group; and R<7> represents a hydrogen atom or when R represents a group -CH2OH then R<7> may also represent a hydroxyl group. The compounds may be used to control nematode, acarine, insect or other pests.