发明名称 Process for producing fat emulsion
摘要 Stable homogeneous fatty emulsions containing amphotericin B are prepared. According to one embodiment, amphotericin B is decrystallized using an acid and ethanol and then homogeneously dispersed in a lipid, following which it is emulsified. According to a second embodiment, amphotericin B crystals are kneaded until their presence can no longer be confirmed and the decrystallized amphotericin B is thereafter uniformly dispersed in a lipid and, thereafter, emulsified.
申请公布号 US5534502(A) 申请公布日期 1996.07.09
申请号 US19950418861 申请日期 1995.04.07
申请人 NIPPON SHINYAKU CO. LTD. 发明人 SEKI, JUNZO;YAMAMOTO, HIROFUMI;YAMANE, SHUJI;TAKAHASHI, YUTAKA;USHIMARU, KOUICHI
分类号 A61K9/00;A61K9/107;A61K9/19;A61K47/10;A61K47/26;(IPC1-7):A61K31/20;A61K31/44;A61K47/30;A61K47/44 主分类号 A61K9/00
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