发明名称 |
Process for producing fat emulsion |
摘要 |
Stable homogeneous fatty emulsions containing amphotericin B are prepared. According to one embodiment, amphotericin B is decrystallized using an acid and ethanol and then homogeneously dispersed in a lipid, following which it is emulsified. According to a second embodiment, amphotericin B crystals are kneaded until their presence can no longer be confirmed and the decrystallized amphotericin B is thereafter uniformly dispersed in a lipid and, thereafter, emulsified.
|
申请公布号 |
US5534502(A) |
申请公布日期 |
1996.07.09 |
申请号 |
US19950418861 |
申请日期 |
1995.04.07 |
申请人 |
NIPPON SHINYAKU CO. LTD. |
发明人 |
SEKI, JUNZO;YAMAMOTO, HIROFUMI;YAMANE, SHUJI;TAKAHASHI, YUTAKA;USHIMARU, KOUICHI |
分类号 |
A61K9/00;A61K9/107;A61K9/19;A61K47/10;A61K47/26;(IPC1-7):A61K31/20;A61K31/44;A61K47/30;A61K47/44 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|