| 发明名称 |
Composition for inserting nucleic acid complexes into higher eucaryotic cells |
| 摘要 |
Composition for the transfection of higher eukaryotic cells with a complex of nucleic acid and substance which has affinity for nucleic acids and is optionally conjugated with an internalisation factor for these cells. The composition contains an endosomolytic agent which is either a free or a bound virus or a virus component or a viral or non-viral peptide with endosomolytic properties. <IMAGE> |
| 申请公布号 |
AU671084(B2) |
申请公布日期 |
1996.08.15 |
| 申请号 |
AU19920026526 |
申请日期 |
1992.09.28 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;THE UNIVERSITY OF NORTH CAROLINA |
发明人 |
DAVID CURIEL;ERNST WAGNER;MATT COTTEN;KURT ZATLOUKAL;CHRISTIAN PLANK;MAX L. BIRNSTIEL;BERND OBERHAUSER;WALTER G. M SCHMIDT |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K38/21;A61K38/36;A61K39/44;A61K47/48;A61K48/00;A61P31/12;A61P35/00;C07K14/005;C07K14/075;C07K14/095;C07K14/11;C07K14/15;C07K14/16;C07K14/56;C07K14/775;C07K14/79;C07K16/00;C07K16/28;C12N5/10;C12N7/04;C12N15/34;C12N15/41;C12N15/44;C12N15/87;(IPC1-7):C12N7/04;C07K13/00;C07K15/18;C12N15/11 |
主分类号 |
C12N15/09 |
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