APPARATUS AND METHOD FOR DELIVERING A NUCLEOTIDE INTO CELL NUCLEI
摘要
The invention presents a system for introducing nucleotides into cells in intact tissue in vitro or in vivo. The invention operates by subjecting the cells to high pressure so that the cells take up the nucleotides from the extracellular space, whereupon the nnucleotides are localized in the cells' nuclei. A transfection rate of greated than 90 % can be achieved using the invention.
申请公布号
WO9634967(A1)
申请公布日期
1996.11.07
申请号
WO1996US06271
申请日期
1996.05.03
申请人
BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UN