4-substituted 17-beta-(cyclopropyloxy)androst-5-EN-3-beta-OL and related compounds useful as C17-20 lyase inhibitors

摘要

This invention is directed to 4-substituted 17 beta -(cyclopropyloxy)androst-5-en-3 beta -ols and related compounds and also to a method for using such compounds in the treatment of androgen-dependent disorders. The ethers are prepared by using the Simmons-Smith reaction and an appropriate vinyl ether.