EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5'alpha'-ANDROS T-1-ENE-17'beta'-CARBOXAMIDE.

摘要

The present invention relates to the epimers: (22R)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5'alpha'-androst -1-ene-17'beta'-carboxamide and (22S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5'alpha'-androst -1-ene-17'beta'-carboxamide useful as inhibitors of testosterone 5'alpha'-reductase enzyme, to a process for their preparation and to pharmaceutical compositions containing them.