| 发明名称 |
Sata and other thiol precursors |
| 摘要 |
The present invention is directed to methods for using reagents to generate and stabilize thiols derived from thiol precursors in order to permit more effective reactions with thiol-reactive substances such as liposomes, proteins and antibodies. These methods provide greatly improved conjugates for utilization in various in vivo and in vitro applications.
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| 申请公布号 |
US5646256(A) |
申请公布日期 |
1997.07.08 |
| 申请号 |
US19940308765 |
申请日期 |
1994.09.19 |
| 申请人 |
BECTON, DICKINSON AND COMPANY |
发明人 |
SHACKELFORD, WILLIAM;READIO, JOSEPHINE;MOORE, SAMUEL L.;RUTNER, HERMAN |
| 分类号 |
A61K9/127;A61K47/48;C07C319/02;C07C319/26;C07C323/60;(IPC1-7):C07K17/06;G01N33/53;G01N33/543 |
主分类号 |
A61K9/127 |
| 代理机构 |
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