IMMUNOLOGICAL REJECTION OF TRANSFECTED TUMOUR CELLS
摘要
The present invention provides a method of inducing an immune response against human tumour cells which can be used in the treatment of tumours in humans. The method involves transfecting the tumour cells with a polynucleotide encoding a glycosyltransferase. The glycosyltransferase may be selected from alpha -1,3 galactosyltransferase, alpha -N-acetyl-D-galactosaminyltransferase and alpha -D-galactosyltransferase.
申请公布号
WO9738109(A1)
申请公布日期
1997.10.16
申请号
WO1997AU00214
申请日期
1997.04.03
申请人
ST. VINCENT INSTITUTE OF MEDICAL RESEARCH;ST. VINCENT'S HOSPITAL;POWER, DAVID, ANTHONY;KEMP, BRUCE, ERNEST