发明名称 |
MELANOMA ASSOCIATED PEPTIDE ANALOGUES AND VACCINES AGAINST MELANOMA |
摘要 |
The present invention is concerned with cancer treatment and diagnosis, especially with melanoma associated peptide analogues with improved immunogenicity, epitopes thereof, vaccines against melanoma, tumour infiltrating T lymphocytes recognizing the antigen and diagnostics for the detection of melanoma and for the monitoring of vaccination. The peptides according to the invention can be exploited to elicit native epitope-reactive CTL. Usage of said peptides with improved immunogenicity may contribute to the development of CTL-epitope based vaccines in viral disease and cancer.
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申请公布号 |
WO9802538(A1) |
申请公布日期 |
1998.01.22 |
申请号 |
WO1997EP03712 |
申请日期 |
1997.07.08 |
申请人 |
AKZO NOBEL N.V.;FIGDOR, CARL, GUSTAV;ADEMA, GOSSE, JAN |
发明人 |
FIGDOR, CARL, GUSTAV;ADEMA, GOSSE, JAN |
分类号 |
G01N33/574;A61K38/00;A61K39/00;A61K51/08;A61P35/00;C07K14/47;C07K14/705;C07K16/18;C07K16/30;C12N15/09;C12N15/11;G01N33/68;(IPC1-7):C12N15/11 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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