发明名称 |
DETECTION OF NUT ALLERGIES |
摘要 |
The present invention relates to a polypeptide comprising an antigenic fragment having a sequence of at least seven amino acids from a hydrophilic domain of an oil body-associated protein, wherein the polypeptide comprises a truncated hydrophobic domain of the oil body-associated protein or does not comprise such a domain, and wherein the oil body-associated protein is selected from the group comprising oleosin, caleosin and steroleosin, to a pharmaceutical composition or a vaccine comprising the polypeptide, to a complex comprising the polypeptide and an antibody bound thereto, to a medical or diagnostic device comprising the polypeptide, to a nucleic acid encoding the polypeptide or a cell comprising said nucleic acid, to a test kit comprising the polypeptide, and to a method for detecting an antibody which binds to the polypeptide. |
申请公布号 |
US2016320407(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201615143011 |
申请日期 |
2016.04.29 |
申请人 |
EUROIMMUN Medizinische Labordiagnostika AG |
发明人 |
Ehlers Anna;Michel Yvonne;Rohwer Stefanie;Suer Waltraud;Unger Mandy |
分类号 |
G01N33/68;G01N33/543;C07K14/415 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
1. A polypeptide comprising an antigenic fragment having a sequence of at least seven amino acids from a hydrophilic domain of an oil body-associated protein,
wherein the polypeptide comprises a truncated hydrophobic domain of the oil body-associated protein or does not comprise such a domain, and wherein the oil body-associated protein is selected from the group comprising oleosin, caleosin and steroleosin. |
地址 |
Lübeck DE |