发明名称 Compounds of boronic acids a process for their preparation and pharmaceutical compositions containing them
摘要 The invention concerns a compound of formula (I): (I) in which: R1, R2, R'1, R'2, identical or different, represent a hydrogen, halogen atom, an alkyl, alkoxy, hydroxy nitro or trihalogenomethyl group, or R1, R2, (R'1, R'2) form together with the benzene nucleus which bears them a naphthyl or anthracenyl group; X represents C=T, SO2, CH2 or X-A1-X represents a group (a) in which T represents an oxygen or sulphur atom; Y, Y' represent an oxygen atom or a NR4 group; A1 represents any one of the groups as defined in the description; A2, A3 represent an alkyl group or a single bond; A4, A'4, identical or different, represent -(CH2)n or -CH=CH-; R3, R'3 are such as defined in the description; Ra, Rb represent a hydrogen atom or an alkyl group. The invention also concerns its isomers as well as its additive salts to a pharmaceutically acceptable base. The invention is useful for the preparation of medicines.
申请公布号 ZA9800440(B) 申请公布日期 1998.07.29
申请号 ZA19980000440 申请日期 1998.01.20
申请人 ADIR ET COMPAGNIE. 发明人 ALEX CORDI;PATRICE DESOS;GHANEM ATASSI;ALAIN PIERRE
分类号 C07F5/02 主分类号 C07F5/02
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