发明名称 |
Nucleic acid construct for the cell cycle regulated expression of structural genes |
摘要 |
<p>The invention refers to a nucleic acid construct comprising at least one activator sequence, at least one chimeric promoter module comprising a nucleotide sequence which binds a protein of the E2F family and a protein of the CDF-1 family, and at least one structural gene, wherein said chimeric promoter modul causes an up-regulation of gene expression in the cell cycle later than the B-myb promoter but earlier than the cdc25C promoter, and the protein CDF-1.</p> |
申请公布号 |
EP0859008(A2) |
申请公布日期 |
1998.08.19 |
申请号 |
EP19980102812 |
申请日期 |
1998.02.18 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
MUELLER, ROLF, PROF. DR.;LIU, NINGSHU;ZWICKER, JOERK, DR.;SEDLACEK, HANS-HARALD, PROF. DR. |
分类号 |
A61K48/00;C07K14/47;C12N15/85;(IPC1-7):C07K14/47 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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