| 发明名称 |
ANTICARCINOGENIC VACCINE AND METHOD OF OBTAINING SAME |
| 摘要 |
<p>Tumor vaccine and process for the preparation thereof. The tumor vaccine contains tumor cells at least some of which contain at least one MHC-I-haplotype of the patient on the cell surface, and which are charged with one or more peptides binding to the MHC-I molecule in such a way that the tumor cells are recognized as foreign by the patient's immune system in context with the peptides and trigger a cellular immune response. The charging is carried out in the presence of a polycation such as polylysine.</p> |
| 申请公布号 |
PL326756(A1) |
申请公布日期 |
1998.10.26 |
| 申请号 |
PL19960326756 |
申请日期 |
1996.11.21 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
SCHMIDT WALTER;BIRNSTIEL MAX;SCHWEIGHOFFER TAMAS;STEINLEIN PETER;BUSCHLE MICHAEL |
| 分类号 |
C12N5/10;A61K31/00;A61K35/12;A61K35/14;A61K35/26;A61K38/00;A61K38/19;A61K38/21;A61K39/00;A61K39/02;A61K39/12;A61K39/145;A61K39/39;A61K48/00;A61P35/00;C07K7/06;C07K14/725;C07K14/74;C12N5/071;C12N5/09;(IPC1-7):A61K35/14 |
主分类号 |
C12N5/10 |
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