A PROCESS FOR PREPARING A CONTROLLED RELEASE COMPOSITION

摘要

A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which compri ses granulating the active ingredient with a molten matrix material or with a matrix material while it is being melted and with optional additional inactive material s at a first elevated temperature, then cooling and screening the granulate, forming a fluidized bed of the resulting material at a second elevated temperature, and recovering t he resulting product; and the product formed by the process.