TEST-INFECTING CULTURE IN ASSAY OF IMMUNOGENICITY OF ANTHRAX VACCINES, EFFECTIVENESS OF AGENTS FOR EMERGENCY PROPHYLAXIS AND TREATMENT OF PATIENTS WITH ANTHRAX

摘要

FIELD: medicine, microbiology, immunology. SUBSTANCE: invention relates to the use of the known strain Bacillus anthracis 81/1 as the high-virulent test-infecting culture for evaluation of immunogenicity of vaccines CTê in vaccinated animal based on immunity index and this strain can be useful for this aim. The protection percent as a difference between percent of survived vaccinated animals and control ones is 7.0 <EMI ID=0.276 HE=3 WI=3 TI=CHI> 5.9 at the infection dose 10 DCL and 42 <EMI ID=0.277 HE=3 WI=3 TI=CHI> 9.0 at the infection dose 50 DCL. EFFECT: improved method of assay. 4 tbl, 3 ex