| 发明名称 |
ADN, POLIPEPTIDO, CELULA, COMPOSICION Y VACUNAS CONTRA LA TOXINA DE LA DIFTERIA. |
| 摘要 |
A DNA encoding an immunologically cross-reactive form of diphtheria toxin Fragment A, wherein the codons corresponding to Val-147 and Glu-148 of naturally-occurring diphtheria toxin are deleted from the DNA.
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| 申请公布号 |
ES2142346(T3) |
申请公布日期 |
2000.04.16 |
| 申请号 |
ES19930913897T |
申请日期 |
1993.05.17 |
| 申请人 |
THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
COLLIER, R., JOHN;KILLEEN, KEVIN;MEKALANOS, JOHN |
| 分类号 |
C12N15/09;A61K38/00;A61K39/05;A61K39/385;A61K47/48;A61P31/04;C07H21/04;C07K14/34;C07K19/00;C12N1/21;C12N15/31;C12N15/54;C12P21/02;C12R1/19;(IPC1-7):C12N15/54;C12N5/10;C12N9/10;A61K38/45 |
主分类号 |
C12N15/09 |
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