DEVICES FOR AND METHODS OF TREATMENT OF METABOLIC SYNDROMES

摘要

Devices for and methods of treatment of metabolic syndromes are disclosed. Namely, the presently disclosed devices and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic syndromes. In some embodiments, the devices include multilayered bioadhesive patches delivered orally by dissolvable ingestible capsule, wherein various mechanisms are provided for anchoring the bioadhesive patches to the duodenal mucosa.

主权项

1. A method for applying a physical barrier to the gastrointestinal (GI) tract of a subject between the intestinal lining and the luminal contents, wherein the physical barrier has one or more of the following effects or characteristics: (a) is created in situ; (b) comprises one or more discrete and non-contiguous components; and (c) preserves significant nutrient absorption capacity within the intestines of the subject; and combinations thereof.