发明名称 INDOLE COMPOUND.
摘要 [Problem] To provide a compound useful as a MT1 and/or MT2 receptor agonist. [Solution] The present inventors have studied on MT1 and/or MT2 receptor agonists, and have confirmed that indole compounds have the activity. As a result, the present invention is accomplished. That is, a compound represented by formula (I) or a salt thereof according to the present invention has a MT1 and/or MT2 receptor agonistic activity and has a low ability of migrating into the central nervous system. Therefore, the compound or a salt thereof can be used as a peripheral MT1 and/or MT2 receptor agonist, and therefore can be used as a therapeutic and/or prophylactic agent for urinary incontinence, particularly stress urinary incontinence and mixed urinary incontinence.
申请公布号 MX2016009180(A) 申请公布日期 2016.10.05
申请号 MX20160009180 申请日期 2015.01.13
申请人 ASTELLAS PHARMA INC. 发明人 Takatoshi KANAYAMA;Shunichiro MATSUMOTO;Tomoyuki SAITO;Shigeo MATSUI;Hiroaki TANAKA;Kazuhiro YOKOYAMA;Tekafumi SHIMIZU;Chiharu MORI
分类号 C07D209/16;A61K31/4045;A61K31/4155;A61K31/422;A61K31/427;A61K31/454;A61K31/497;A61K31/506;A61P13/10;A61P43/00;C07D401/12;C07D403/12;C07D417/12 主分类号 C07D209/16
代理机构 代理人
主权项
地址