发明名称 |
Anvendelse av et DNA-fragment, samt komplement¶re kjeder, derivater og deler derav |
摘要 |
The inventon relates to antibodies that react with a variant epilope in the extracellular region of a variant CD44 polypeptide, wherein the variant epitope has the amino acid sequence: I S S T I S T T P R A P D H T K Q N Q D W T Q W N P S H S N P E V L L Q T T T R M T D V D R N G T T A Y E G N W N P E A H P P L I H H E H H E E E E T P H S T S T I O A T P S S T T E E T A T Q K E Q W F G N R W H E G Y R Q T P R E D S H S T T G T A A A S A H T S H P M Q G R T T P S P E D S S W T D F F N P I S H P M G R G H Q A G R R (residues 53-219 of SEQ ID NO:4). Methods of using the antibodies to identify variant epitopes also are provided.
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申请公布号 |
NO310661(B1) |
申请公布日期 |
2001.08.06 |
申请号 |
NO20000001668 |
申请日期 |
2000.03.31 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM |
发明人 |
HERRLICH, PETER;PONTA, HELMUT;GUENTHERT, URSULA;MATZKU, SIEGFRIED;WENZEL, ACHIM |
分类号 |
A61K38/00;A61K38/17;A61K39/395;A61P35/00;A61P35/04;C07K;C07K14/00;C07K14/47;C07K14/705;C07K14/73;C07K14/82;C07K16/00;C07K16/28;C07K16/30;C12N5/10;C12N15/09;C12N15/12;C12N15/13;C12P21/02;C12P21/08;G01N33/53;G01N33/574;G01N33/68;(IPC1-7):C07K14/725 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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