Production of malonic diesters, used e.g. in the synthesis of pharmaceuticals, plastics, plant protection agent, perfume or aroma, by catalytic ester exchange with alcohol is carried out continuously

摘要

Production of malonic diesters (I) by ester exchange from different malonic diesters (II) with a 1-30C linear or branched alkyl or alkenyl, cycloalkyl or aralkyl alcohol (III) in the presence of an ester exchange catalyst is carried out continuously. Production of malonic diesters of formula (I) by ester exchange from different malonic diesters of formula (II) with a 1-30C linear or branched alkyl or alkenyl, cycloalkyl or aralkyl alcohol of formula R 1>OH (III) in the presence of an ester exchange catalyst is carried out continuously. [Image] R 1>, R 2>, R 3>1-30C alkyl or alkenyl, cycloalkyl or aralkyl.